KSM  Clinic

272-bed acute care Hospital
        Where  Patients  Matter

                                                                         

AABB Criteria for Umbilical Cord Blood (UCB) Clinical Use in Patients:

  • Informed Consent (preferably from both parents)
  • Closed-system collection (Open-system /CBR-CA)
  • Sterile Volume >70 ml (anti-coagulant and test sample excluded)
  • Mother Afebrile
  • No Complications (Pre-Eclampsia, Eclampsia, etc.)
  • Labor <24 Hours
  • Infant Weight >2,500 g
  • APGAR Score >8
  • No Malformations

 FDA approved umbilical cord blood stem cells in Bone Marrow Transplants for various disorders

 

UMBILICAL  CORD  BLOOD  COLLECTION:

After obtaining informed consent from the parents of the baby, umbilical cord blood (UCB)  is collected immediately after the delivery.

The AABB criteria for collection of UCB for clinical use in patients, as above, is strictly enforced.

Briefly, a 16-G needle of a standard blood-donor set, containing CPDA anticoagulant, is inserted into the umbilical vein, at the betadine-cleaned insertion site.  In a closed-system, UCB runs down by gravity into the CPDA-bag.

Since UCB volume varies (35-110 ml), CPDA is preferred over ACD anticoagulant, as the former is volume independent and isotonic with neutral pH.

In accordance with AABB, "freshly-collected" cord blood is processed in the Clinic laboratory.  A small sample (about 10 ml) is saved for various tests and cultures.                                                                                        

                   

FDA's responsibilities comprise:

  • Foods (except meat, alcoholic beverages, and tobacco)
  • Drugs (including items with drug claims)
  • Biologics (vaccines)
  • Veterinary Drugs
  • Medical Devices
  • Radiological Devices
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